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Visibility and Response Across Your Entire Microsoft Security Ecosystem

Maximize your Microsoft investment with 24/7 Managed Detection and Response with our Microsoft security solutions. As part of eSentire MDR for Microsoft, we identify, contain, respond to and remediate threats across Microsoft Sentinel and Defender for Endpoint, Identity, Office 365 and Cloud Apps services.

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Secure Your Microsoft Investment with eSentire MDR for Microsoft

Although organizations are investing in Microsoft 365 E5 to get the most security capabilities and features for their investment, many fail to take advantage of Microsoft’s advanced and cost-effective cybersecurity solutions, largely due to a lack of in-house expertise and resources to properly optimize and manage these tools.

At eSentire, we share Microsoft’s zero-trust approach to cybersecurity and firmly believe that you need a certified, experienced, and trusted partner to protect your investment in the Microsoft ecosystem. As part of eSentire MDR for Microsoft security solutions, we offer complete multi-signal MDR across your Microsoft Sentinel and Defender for Endpoint, Identity, Office 365 and Cloud Apps services.

eSentire MDR with Microsoft Defender XDR

Stop advanced threats and minimize the risk of business disruption across your users, endpoints, and cloud applications.

Microsoft Defender for Endpoint

Endpoint protection, detection, response, and remediation

Microsoft Defender for Office 365

Mitigate the risk of phishing and business email compromise

Microsoft Defender for Identity

Investigate and respond to compromised identities and insider threats

Microsoft Defender for Cloud Apps

Rich visibility into data and user activity across your cloud SaaS applications

eSentire MDR with Microsoft Sentinel

Critical threat visibility and 24/7 monitoring across multi-cloud, and hybrid environments. Detect and investigate threats in:

  • Azure Active Directory
  • Microsoft Defender For Cloud
  • AWS
  • Google Cloud Platform
  • Google Workspace
  • Existing Security Controls and Network Infrastructure

Our MDR for Microsoft offering includes:

  • 24/7 Microsoft Ecosystem Visibility
  • Elite Threat Hunting and Original Research
  • 24/7 Security Event Monitoring
  • Certified Microsoft Experts
  • 24/7 Threat Detection and Investigation
  • 24/7 Live SOC Cyber Analyst Support
  • Proprietary Threat Detection Content and Microsoft Runbooks
  • 24/7 Threat Disruption and Complete Response On Your Behalf

The result? We stop threats across your Microsoft ecosystem before they disrupt your business operations.


Questions to Consider When Evaluating an MDR for Microsoft Provider

Learn the top questions you should ask as you evaluate your next MDR for Microsoft provider.


RFP/RFI Sample Questions for Microsoft MDR Providers

Get an in-depth template you can use when selecting an MDR vendor to secure your Microsoft ecosystem.

Microsoft Virtual Summit

Unlocking Your Microsoft 365 Investment with Managed Detection & Response

As security teams are asked to do more with less, cybersecurity leaders need to take advantage of the threat detection and investigation capabilities Microsoft Defender XDR and Sentinel have to offer.

Microsoft offers a cost-effective and highly integrated security stack that covers endpoint, email, cloud, identity, and more. So, many security leaders are choosing to replace their legacy tools with Microsoft’s advanced security stack to get the most out of their Microsoft 365 investment.

The virtual summit agenda features:

  • Unlocking Your Microsoft 365 Investment
    Presented by Kurtis Armour, VP Product Management at eSentire
  • Driving Cybersecurity Cost Efficiencies and Tool Consolidation with Microsoft
    Presented by Dana Mitchell, National Enterprise Security Advisor, Microsoft
  • A Fireside Chat with Michael Smith, Vice President IT Operations at HKS and Rich Raether, CIO at Quarles & Brady LLP
    Hosted by Erin McLean, CMO, eSentire

What You Can Expect from eSentire MDR for Microsoft

Complete Microsoft Ecosystem Visibility and Optimization

Unparalleled Threat Response and Remediation

Maximum ROI on Microsoft Cloud Investments

Highly Certified Expertise


Complete Microsoft Ecosystem Visibility and Optimization


Centralize visibility and account for risks across your Microsoft cloud ecosystem. Get expert guidance and support from eSentire’s Microsoft team to optimize your cybersecurity controls and overall posture.


Unparalleled Threat Response and Remediation


Build a resilient security operation by combining cutting-edge XDR technology and our security expertise to stop and remediate cyber threats across endpoint, email, cloud, and identity vectors.


Maximum ROI on Microsoft Cloud Investments


Unlock the full potential of the controls and tools that exist within your investments in Microsoft Defender XDR and Microsoft Sentinel. Plus our cybersecurity experts become a 24/7 extension of your team.


Highly Certified Microsoft Expertise


As an active member of the Microsoft Intelligent Security Association (MISA) we have achieved MXDR status with Microsoft, and are a Microsoft Security Solutions Partner. We have managed 250+ Microsoft MDR deployments.

Not All MDR for Microsoft is Created Equal

At eSentire, we go beyond the market’s capabilities in Response.

We don’t just detect and investigate threats across your Microsoft ecosystem – we actively respond. That means we’re isolating hosts, containing threats, and remediating security incidents on your behalf.

As part of our complete response across Microsoft Defender XDR and Microsoft Sentinel, you should expect:

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Why Choose eSentire to Secure Your Microsoft Ecosystem

Response and Remediation

We prioritize the R in MDR. We actively respond to threats on your behalf while the other guys overload you with alerts to investigate. That means we are isolating hosts, containing threats and remediating security incidents across your Microsoft suite.

Certified and Experienced

We are a Microsoft Security Solutions Partner and are proud Microsoft Intelligent Security Association (MISA) members, demonstrating our leadership in multi-cloud security and Microsoft expertise. We’ve overseen 250+ successful Microsoft MDR deployments to date.

Unique Intelligence, Powered by our Threat Response Unit

Supercharge your Microsoft security investments with improved detection and response capabilities, our proprietary threat content, runbooks, and AI/ML innovations created by our elite Threat Response Unit (TRU).

Time to Value

Zero-install onboarding with time to value in days, not weeks or months. Disciplined service deployment and robust escalation processes to ensure complete response.

Complete Coverage

End-to-end cyber risk mitigation and coverage across our Exposure Management, Managed Detection and Response and Incident Response services.


Leverage your existing licenses and investment in Microsoft to optimize your security posture with enhanced visibility, controls and response capabilities.

Total Cost of Ownership Benefits

By combining eSentire MDR with your existing investment in the Microsoft ecosystem, you can significantly reduce overall security spend without sacrificing quality. See how you can reduce your security total cost of ownership (TCO), broken down by technology, implementation and management costs.

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Total Cost of Ownership Table Image 1 Total Cost of Ownership Table Image 1 - Mobile
Total Cost of Ownership Table Image 1 Total Cost of Ownership Table Image 1 - Mobile
Total Cost of Ownership Table Image 1 Total Cost of Ownership Table Image 1 - Mobile

Security Leaders Count on eSentire MDR for Microsoft

As more traffic and workloads move to the Microsoft stack, cybersecurity leaders can count on eSentire for complete, multi-signal coverage. We’ve managed 250+ successful Microsoft MDR customer deployments to date and currently have 150,000+ endpoints under management with Microsoft Defender for Endpoint across our global customer base.

At eSentire, we don’t just detect and investigate threats across your Microsoft environment – we provide complete and robust response across your entire attack surface.



Quarles & Brady is a multi-practice law firm that was looking to adopt Microsoft 365 but didn’t have sufficient in-house expertise to operationalize the tools.

Outsourcing cybersecurity operations to eSentire allowed the firm to have:

  • 24/7 Threat Detection and Response across the company’s large IT environment
  • Access to cybersecurity experts that act like an extension of their team
  • Complete visibility across the attack surface
  • Best-in-class tools at a cost-effective price
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See how eSentire worked with Venerable to mitigate cyber risks and address their multi-cloud cybersecurity strategy with:

  • 24/7 Threat Detection and Investigation with eSentire MDR for Log to identify and investigate cyber threats within Venerable’s AWS environment
  • Cloud Security Posture Management to reduce their risk by improving cloud visibility, tracking critical assets, and monitoring for misconfigurations, policy notifications and security vulnerabilities
  • eSentire MDR for Microsoft to ensure complete detection, response, and remediation across endpoints.

Industry Leading Research and Threat Discoveries

We have discovered some of the most dangerous threats and nation state attacks in our space – including the Kaseya MSP breach and the malicious more_eggs malware.

Microsoft has even credited us with identifying the group responsible for the Google Site malware that transitioned to target Microsoft and Amazon Web Services customers. See how we’re protecting businesses globally and check out our latest security advisories.


Hackers Flood the Web with 100,000 Malicious Pages, Promising Professionals Free Business Forms, But Delivering Malware, Reports eSentire


Ready to get started with eSentire MDR for Microsoft?

We’re here to help! Submit your information and an eSentire representative will be in touch to demonstrate how eSentire MDR for Microsoft stops threats across your Microsoft ecosystem before they impact your business.